in anesthetized dogs with experimentally induced metabolic acidosis.
Metabolic acidosis is an important abnormality in ill and injured dogs and cats.
Metabolic acidosis was evident in 49% of the animals in which a blood gas was performed during the 13‐month period of this study. These patients included those presenting to the emergency room, intensive care unit patients, anesthetized patients, and specialty service patients. A wide variety of primary disease processes was present (Table ). The most common complaints in combined arterial and venous samples of dogs were neoplasia and surgery. On review of the records, the most common reason for surgery in this population was neoplasia, and blood gas analysis was performed intraoperatively. Not surprisingly, in the canine group of venous samples, surgery was an uncommon problem and neoplasia was far less frequently reported, although it remained the most common problem of the canine group. There may be several causes of metabolic acidosis in patients with neoplasia including Type B lactic acidosis and secondary organ function impairment. In contrast to dogs, renal disease was the most frequent disease process in cats in this study. Renal disease is well recognized to cause metabolic acidosis by several potential mechanisms. It cannot be determined if the acid base abnormalities identified in this study were primarily due to the underlying diseases present, the treatment provided, or both. Unfortunately, it is not possible to assess the incidence of metabolic acidosis in specific disease states in the current study, but these results do indicate that metabolic acidosis is a common acid base abnormality in those patients for which clinicians elect to perform blood gas analysis.
Arterial and venous blood samples were analyzed together in this study, using venous results for the acid base diagnosis. Because arterial acid base parameters, in particular PCO2, are different from venous parameters, there is the potential that respiratory alkalosis may have been falsely diagnosed in some arterial samples. Interestingly, when the venous samples were analyzed separately, there was an increase in the proportion of cats and dogs classified as having a combined metabolic acidosis and a respiratory alkalosis. Almost all of the arterial samples were collected under anesthesia, and the PCO2 is likely to have been influenced by respiratory depressant drugs. Accordingly, when the venous samples were analyzed separately from the combined arterial and venous samples, the major difference was a reduction in the number of cases diagnosed with metabolic acidosis and concurrent respiratory acidosis. This is not an unexpected finding, but must be taken into account if trying to extrapolate our findings to another patient population.
Metabolic acidosis with pneumatic trousers in hypovolemic dogs
Metabolic Acidosis with Pneumatic Trousers in Hypovolemic Dogs